IKZF1 anticorps (N-Term)

N° du produit ABIN2668828

Il existe 1 publication pour ce produit. L’anticorps anti-IKZF1 Monoclonal Souris est utilisé pour la détection de IKZF1 dans des échantillons de Souris. Il a été validé pour WB, ChIP et ChIP-seq.

Aperçu rapide pour IKZF1 anticorps (N-Term) (ABIN2668828)

Antigène: IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IKZF1 est non-conjugé

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Clone: 2A9

Détail du produit anti-IKZF1 anticorps

Épitope: N-Term

Fonction: Ikaros antibody (mAb) (Clone 2A9)

Purification: Protein G Chromatography

Immunogène: This Ikaros antibody was raised against a recombinant protein corresponding to the N-terminal half of mouse Ikaros.

Isotype: IgG

Information d'application

Indications d'application: ChIP: 4 μg per ChIP ChIP-Seq: 4 μg each WB: 0.5 - 2 μg/mL dilution ChIP-Seq validation was performed by Active Motif's Epigenetics Services, the complete data set is available in the UCSC Genome Browser by clicking here.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-IKZF1 (ABIN2668828)

Yeung, Chung, Guess, Bell, Leinwand: "Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos." dans: Nucleic acids research, Vol. 40, Issue 15, pp. 7303-18, (2012) (PubMed).

Détails sur IKZF1

Antigène: IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Autre désignation: Ikaros

Sujet: Ikaros is a transcription factor that plays a critical role in the control of lymphohematopoiesis and immune regulation. All Ikaros isoforms share a common C-terminal domain that contains a transcription activation motif and two zinc finger motifs required for hetero- and homo-dimerization among the Ikaros isoforms, and for interactions with other proteins. Ikaros is abundantly expressed in pituitary mammosomatotrophs, where it deacetylates Histone H3 sites on the proximal growth hormone (GH) promoter to silence gene expression.

Poids moléculaire: 62 kDa

ID gène: 22778

NCBI Accession: NM_001025597

Pathways: Production of Molecular Mediator of Immune Response