MTF2 anticorps

N° du produit ABIN2668833

Cet anticorps Souris Monoclonal détecte spécifiquement MTF2 dans WB. Il présente une réactivité avec des échantillons de Humain.Il a été cité dans 1 publication.

Aperçu rapide pour MTF2 anticorps (ABIN2668833)

Antigène: MTF2 (Metal Response Element Binding Transcription Factor 2 (MTF2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MTF2 est non-conjugé

Application: Western Blotting (WB)

Clone: 3A9

Détail du produit anti-MTF2 anticorps

Fonction: PCL2 antibody (mAb) (Clone 3A9)

Purification: Protein G Chromatography

Immunogène: This PCL2 antibody was raised against a recombinant protein corresponding to amino acids 103 - 327 of mouse PCL2.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-MTF2 (ABIN2668833)

Li, Isono, Yamada, Endo, Endoh, Shinga, Mizutani-Koseki, Otte, Casanova, Kitamura, Kamijo, Sharif, Ohara, Toyada, Bernstein, Brockdorff, Koseki: "Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes." dans: Molecular and cellular biology, Vol. 31, Issue 2, pp. 351-64, (2010) (PubMed).

Détails sur MTF2

Antigène: MTF2 (Metal Response Element Binding Transcription Factor 2 (MTF2))

Autre désignation: PCL2

Sujet: PCL2 (Polycomb-like 2, MTF2, M96) is a member of the Polycomb PRC2 protein complex and is important in cell fate decisions and may play a role in recruitment of PRC2 to target genes and histone methylation. PCL2 regulates gene expression patterns controlling self-renewal and commitment in embryonic stem cells and plays a critical role in ESC differentiation and self-renewal. PCL2 contains two PHD fingers.

Poids moléculaire: 70 kDa

ID gène: 17765

NCBI Accession: NP_038855

Pathways: Stem Cell Maintenance