ZBTB16 anticorps

N° du produit ABIN2668927

Il existe 3+ publications pour ce produit. L’anticorps anti-ZBTB16 Monoclonal Souris est utilisé pour la détection de ZBTB16 dans des échantillons de Humain et Souris. Il a été validé pour WB, IF, ICC, IP et ChIP.

Aperçu rapide pour ZBTB16 anticorps (ABIN2668927)

Antigène: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ZBTB16 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)

Clone: 2A9

Détail du produit anti-ZBTB16 anticorps

Fonction: PLZF antibody (mAb) (Clone 2A9)

Purification: Protein G Chromatography

Immunogène: This PLZF antibody was raised against a recombinant protein corresponding to full-length mouse PLZF with a GST-Tag.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: PBS pH 7.5 containing 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-ZBTB16 (ABIN2668927)

Felli, Errico, Pedini, Petrini, Puglisi, Bellenghi, Boe, Felicetti, Mattia, De Feo, Bottero, Tripodo, Carè: "AP2α controls the dynamic balance between miR-126&126* and miR-221&222 during melanoma progression." dans: Oncogene, Vol. 35, Issue 23, pp. 3016-26, (2016) (PubMed).

Chapman, Medrano, Chaudhary, Hamra: "NRG1 and KITL Signal Downstream of Retinoic Acid in the Germline to Support Soma-Free Syncytial Growth of Differentiating Spermatogonia." dans: Cell death discovery, Vol. 1, (2015) (PubMed).

Koken, Reid, Quignon, Chelbi-Alix, Davies, Kabarowski, Zhu, Dong, Chen, Chen, Tan, Licht, Waxman, de Thé, Zelent: "Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 19, pp. 10255-60, (1997) (PubMed).

Détails sur ZBTB16

Antigène: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Autre désignation: PLZF

Sujet: PLZF (Promyelocytic Leukemia Zinc-Finger protein) is a member of the POK (POZ and Krüppel) family of transcriptional repressors. PLZF is expressed in early, but not differentiated, hematopoietic cells, and is required for spermatogonial stem cell maintenance. In addition, PLZF regulates genes involved in cellular proliferation and differentiation (cyclin A2, Myc and Hox genes) and targeted deletion of PLZF in mice results in limb and axial skeleton and limb deformations.

Poids moléculaire: 90 kDa

ID gène: 235320

NCBI Accession: NP_001028496

Pathways: Positive Regulation of fat Cell Differentiation