PIWIL2 anticorps

N° du produit ABIN2668966

Il existe 1 publication pour ce produit. L’anticorps anti-PIWIL2 Monoclonal Souris est utilisé pour la détection de PIWIL2 dans des échantillons de Souris. Il a été validé pour WB, ICC, IF et IP.

Aperçu rapide pour PIWIL2 anticorps (ABIN2668966)

Antigène: PIWIL2 (Piwi-Like 2 (PIWIL2))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PIWIL2 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 17-8

Détail du produit anti-PIWIL2 anticorps

Fonction: Mili / PiwiL2 antibody (mAb) (Clone 17.8)

Purification: Protein G Chromatography

Immunogène: This Mili / PiwiL2 antibody was raised against full-length recombinant mouse MILI / PIWIL2 protein.

Isotype: IgG1

Information d'application

Indications d'application: This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91253.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-PIWIL2 (ABIN2668966)

Kirino, Kim, de Planell-Saguer, Khandros, Chiorean, Klein, Rigoutsos, Jongens, Mourelatos: "Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability." dans: Nature cell biology, Vol. 11, Issue 5, pp. 652-8, (2009) (PubMed).

Détails sur PIWIL2

Antigène: PIWIL2 (Piwi-Like 2 (PIWIL2))

Autre désignation: Mili / PiwiL2

Sujet: Mili / PiwiL2 is a member of the PIWI/AGO subfamily of RNA-binding proteins. Mili / PiwiL2 contains a Piwi and an AGO domain and binds a class of RNA called piwi-interacting RNA (piRNA), which are 24 to 30 nucleotides in length and are derived primarily derived from transposons and other repeated sequence elements. Mili / PiwiL2 is required for methylation and inactivation of retrotransposons. Mice deficient in Mili / PiwiL2 are sterile, as it is also required for spermatogenesis. It also positively regulates translation, and is required for germ line stem cell division and differentiation.

Poids moléculaire: 97 kDa

ID gène: 57746

NCBI Accession: NP_001129193

Pathways: Stem Cell Maintenance