HIV-1 Tat anticorps

N° du produit ABIN2669371

Détail du produit anti-HIV-1 Tat anticorps

Antigène: HIV-1 Tat

Reactivité: Human Immunodeficiency Virus (HIV)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIV-1 Tat est non-conjugé

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Specificité: Tat protein clade A and B, GSTTat fusion protein

Attributs du produit: The HIV-1 regulatory protein tat is considered an attractive target for the development of a multicomponent vaccine against HIV-1 infection. The protein is well conserved among different isolates and thus may be less susceptible to mutation leading to the production of escape virus variants. Tat is produced early after infection and it's essential for virus replication and infectivity. Tat protein is also immunogenic and antibodies (Ab) against tat have been correlated with delayed disease progression and may exert protective effects inhibiting HIV replication. Moreover, Tat is efficiently taken up by monocyte-derived dendritic cells, promoting their maturation. Finally, murine vaccination with a biologically active tat protein has been shown to be safe and immunogenic.

Purification: Polyclonal immunoglobulins purified by affinity chromatography.

Immunogène: Recombinant purified HIV-1 tat protein Clade B expressed in E. coli

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in 100 mM sodium citrate, 50 mM Tris and 0.05 % v/v glycerol

Stock: 4 °C

Détails sur HIV-1 Tat

Antigène: HIV-1 Tat

Autre désignation: HIV1 Tat (HIV-1 Tat Produits)

Classe de substances: Viral Protein