ICAM2 anticorps

N° du produit ABIN2688871

Cet anticorps anti-ICAM2 est un anticorps Rat Monoclonal détectant ICAM2 dans FACS, IP, IHC (fro), IHC (p) et BR. Adapté pour Souris. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour ICAM2 anticorps (ABIN2688871)

Antigène: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp ICAM2 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Blocking Reagent (BR)

Clone: 3C4

Détail du produit anti-ICAM2 anticorps

Marque: BD Pharmingen™

Attributs du produit: The 3C4 (mIC2/4) antibody reacts with the mouse ICAM-2 (CD102) cell surface glycoprotein, a ligand for LFA-1. CD102 is constitutively expressed on endothelial cells, T and B lymphocytes, and alveolar walls. It is also expressed on a variety of leukocyte cell lines. CD102 does not appear to be involved in the development of hematopoietic cells. In a model for allergic asthma, endothelial CD102 mediates the transmigration of eosinophils (but not lymphocytes, monocytes, or macrophages) into the airway lumen. The 3C4 (mIC2/4) antibody blocks interactions between ICAM-2 and LFA-1. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

BD Pharmingen™ Purified Rat Anti-Mouse CD102 - Purified - Clone 3C4(mIC2/4) - Isotype Rat IgG2a, κ - Reactivity Ms - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Transfected Cell Line

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-ICAM2 (ABIN2688871)

Gerwin, Gonzalo, Lloyd, Coyle, Reiss, Banu, Wang, Xu, Avraham, Engelhardt, Springer, Gutierrez-Ramos: "Prolonged eosinophil accumulation in allergic lung interstitium of ICAM-2 deficient mice results in extended hyperresponsiveness." dans: Immunity, Vol. 10, Issue 1, pp. 9-19, (1999) (PubMed).

Xu, Bickford, Luther, Carpenito, Takei, Springer: "Characterization of murine intercellular adhesion molecule-2." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 156, Issue 12, pp. 4909-14, (1996) (PubMed).

Xu, Tong, De Fougerolles, Springer: "Isolation, characterization, and expression of mouse ICAM-2 complementary and genomic DNA." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 149, Issue 8, pp. 2650-5, (1992) (PubMed).

Détails sur ICAM2

Antigène: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Autre désignation: CD102

Sujet: Synonyms: ICAM-2