(11 références)-
- Antigène Tous les produits CD15s
- CD15s
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Inconjugué
-
Application
- Flow Cytometry (FACS)
- Marque
- BD Pharmingen™
- Attributs du produit
-
Anti-Sialyl-Le[x] monoclonal antibody (clone CSLEX1) is specific for the α2-3 sialosylated form of lacto-N-fucopentaose III, sialyl Lex (Sle[x]). Sle[x] is expressed on granulocytes, monocytes and both normal and tumor cells of diverse origin. It has been shown to be a ligand for both endothelial leukocyte adhesion molecule-1 (ELAM-1 or E-selectin), and granule membrane protein-140 (GMP-140 or P-selectin).
BD Pharmingen™ Purified Mouse Anti-Human CD15s - Purified - Clone CSLEX1 - Isotype Mouse IgM, κ - Reactivity Hu - 0.1 mg - Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Clone
- CSLEX1
- Isotype
- IgM kappa
-
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Concentration
- 0.5 mg/mL
- Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store undiluted at 4°C.
-
-
: "CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis x." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 14, pp. 6224-8, (1991) (PubMed).
: "The selectin GMP-140 binds to sialylated, fucosylated lactosaminoglycans on both myeloid and nonmyeloid cells." dans: The Journal of cell biology, Vol. 115, Issue 2, pp. 557-64, (1991) (PubMed).
: "ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex." dans: Science (New York, N.Y.), Vol. 250, Issue 4984, pp. 1130-2, (1991) (PubMed).
: "The neutrophil selectin LECAM-1 presents carbohydrate ligands to the vascular selectins ELAM-1 and GMP-140." dans: Cell, Vol. 66, Issue 5, pp. 921-33, (1991) (PubMed).
: "Recognition by ELAM-1 of the sialyl-Lex determinant on myeloid and tumor cells." dans: Science (New York, N.Y.), Vol. 250, Issue 4984, pp. 1132-5, (1991) (PubMed).
: "Requirement for sialic acid on neutrophils in a GMP-140 (PADGEM) mediated adhesive interaction with activated platelets." dans: Biochemical and biophysical research communications, Vol. 172, Issue 3, pp. 1349-56, (1990) (PubMed).
: "An inducible endothelial cell surface glycoprotein mediates melanoma adhesion." dans: Science (New York, N.Y.), Vol. 246, Issue 4935, pp. 1303-6, (1990) (PubMed).
: "The cellular basis of site-specific tumor metastasis." dans: The New England journal of medicine, Vol. 322, Issue 9, pp. 605-12, (1990) (PubMed).
: "Endothelial leukocyte adhesion molecule 1: direct expression cloning and functional interactions." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 5, pp. 1673-7, (1990) (PubMed).
: "Interleukin 1 promotes tumor cell adhesion to cultured human endothelial cells." dans: The Journal of clinical investigation, Vol. 82, Issue 4, pp. 1466-70, (1988) (PubMed).
: "Characterization of sialosylated Lewisx as a new tumor-associated antigen." dans: Cancer research, Vol. 44, Issue 11, pp. 5279-85, (1984) (PubMed).
-
: "CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis x." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 14, pp. 6224-8, (1991) (PubMed).
-
- Antigène
- CD15s
- Abstract
- CD15s Produits
- Sujet
- Synonyms: Sialyl Lewis x
-
Vous êtes ici:
