CD1d anticorps

N° du produit ABIN2689065

Détail du produit anti-CD1d anticorps

Antigène: CD1d (CD1D) (CD1d Molecule (CD1D))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD1d est non-conjugé

Application: Flow Cytometry (FACS)

Marque: BD Pharmingen™

Attributs du produit: Reacts with a glycosylated type I transmembrane α chain (43-49 kDa) non- covalently associated with β2-microglobulin. CD1d is a member of the CD1 family of molecules, which belong to the immunoglobulin superfamily. Sequence homology data classifies the CD1 Molecules into two groups. Group 1 includes CD1a, CD1b and CD1c molecules, group 2 includes CD1d molecules and their homologues in other species. CD1d is expressed on human intestinal epithelial cells (IEC). CD1d42 monoclonal antibody reacts with peripheral blood B cells coexpressing CD19 and CD45RA. It is not seen on CD3[+], or CD45RO[+] cells. Studies suggest that CD1d participates in lipid antigen presentation. Profile of peripheral blood lymphocytes analyzed by flow cytometry

BD Pharmingen™ Purified Mouse Anti-Human CD1d - Purified - Clone CD1d42 (also known as 42.1) - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: CD1d42

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-CD1d (ABIN2689065)

Hong, Scherer, Singh, Mendiratta, Serizawa, Koezuka, Van Kaer: "Lipid antigen presentation in the immune system: lessons learned from CD1d knockout mice." dans: Immunological reviews, Vol. 169, pp. 31-44, (1999) (PubMed).

Somnay-Wadgaonkar, Nusrat, Kim, Canchis, Balk, Colgan, Blumberg: "Immunolocalization of CD1d in human intestinal epithelial cells and identification of a beta2-microglobulin-associated form." dans: International immunology, Vol. 11, Issue 3, pp. 383-92, (1999) (PubMed).

Détails sur CD1d

Antigène: CD1d (CD1D) (CD1d Molecule (CD1D))

Autre désignation: CD1d (CD1D Produits)

Synonymes: anticorps CD1A, anticorps R3, anticorps CD1D, anticorps CD1D1, anticorps CD1d molecule, anticorps CD1D antigen, d polypeptide, anticorps CD1D

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process