LY75/DEC-205 anticorps

N° du produit ABIN2689082

Cet anticorps Souris Monoclonal détecte spécifiquement LY75/DEC-205 dans FACS. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 3+ publications.

Aperçu rapide pour LY75/DEC-205 anticorps (ABIN2689082)

Antigène: LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LY75/DEC-205 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: MG38

Détail du produit anti-LY75/DEC-205 anticorps

Attributs du produit: Reacts with DEC-205, a 205 kDa transmembrane protein with C-type lectin external domains, present on dendritic cells (DC) and some epithelia. It is being described as a multilectin receptor for adsorptive endocytosis. MG38 antibody reacted with mature monocyte-derived DC and also with B cells, monocytes and weakly on T cells and NK cells. Antibody MG38 is useful for the study of DC development. Profile of CD205 (DEC-205), clone MG38, reactivity on monocyte-derived cultured dendritic cells analyzed by flow cytometry. Second step staining with FITC Goat Anti-Mouse IgG/IgM (Cat. No. 555988).

BD Pharmingen™ Purified Mouse Anti-Human CD205 - Purified - Clone MG38 - Isotype Mouse IgG2b - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-LY75/DEC-205 (ABIN2689082)

Guo, Gong, Maric, Misulovin, Pack, Mahnke, Nussenzweig, Steinman: "A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells." dans: Human immunology, Vol. 61, Issue 8, pp. 729-38, (2000) (PubMed).

Kato, Neil, Fearnley, McLellan, Vuckovic, Hart: "Expression of multilectin receptors and comparative FITC-dextran uptake by human dendritic cells." dans: International immunology, Vol. 12, Issue 11, pp. 1511-9, (2000) (PubMed).

Kato, Neil, Clark, Morris, Sorg, Hart: "cDNA cloning of human DEC-205, a putative antigen-uptake receptor on dendritic cells." dans: Immunogenetics, Vol. 47, Issue 6, pp. 442-50, (1998) (PubMed).

Détails sur LY75/DEC-205

Antigène: LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

Autre désignation: CD205

Sujet: Synonyms: DEC-205, Lymphocyte Antigen 75, CLEC13B