ITGA5 anticorps
Aperçu rapide pour ITGA5 anticorps (ABIN2689313)
Antigène
Voir toutes ITGA5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Attributs du produit
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Reacts with the α5 integrin, a dimer of 135/25 kDa, that associates with β1 integrin (CD29) to form VLA-5, a well-established fibronectin receptor that is expressed on many cell types, including fibroblasts, endothelial cells, epithelial cells, platelets, peripheral T cells, the myeloid cell line U937, K562 and some melanoma cell lines. This clone does not inhibit α5β1/ligand binding. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed on a FACScan
BD Pharmingen™ Purified Mouse Anti-Human CD49e - Purified - Clone VC5 - Isotype Mouse IgG1, κ - Reactivity Hu, Pig - 0.1 mg -
Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Isotype
- IgG1 kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store undiluted at 4°C.
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: "Bacterial internalization mediated by beta 1 chain integrins is determined by ligand affinity and receptor density." dans: The EMBO journal, Vol. 12, Issue 5, pp. 1887-95, (1993) (PubMed).
: "The Yersinia pseudotuberculosis invasin protein and human fibronectin bind to mutually exclusive sites on the alpha 5 beta 1 integrin receptor." dans: The Journal of biological chemistry, Vol. 266, Issue 36, pp. 24367-75, (1992) (PubMed).
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- ITGA5 (Integrin, alpha 5 (ITGA5))
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Autre désignation
- CD49e
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Sujet
- Synonyms: Integrin α5 chain
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Pathways
- Integrin Complex
Antigène
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