CEACAM8 anticorps
Aperçu rapide pour CEACAM8 anticorps (ABIN2689375)
Antigène
Voir toutes CEACAM8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Attributs du produit
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Reacts with CD66b, a glycosylphosphatidylinositol (GPI) linked protein with a molecular weight of 100 kD expressed on granulocytes. This molecule was previously clustered as CD67 in the Fourth Human Leucocyte Differentiation Antigen (HLDA) Workshop and renamed CD66b in the Fifth HLDA Workshop. CD66b is a member of the carcinoembryonic antigen (CEA)-like glycoprotein family present on granulocytes and referred to as non-specific cross-reacting antigens (NCA). Granulocyte activation induced with soluble stimulators (calcium ionophore, phorbol myristate acetate, Nformylmethionyl- leucyl-phenylalanine) results in release and increased expression of NCA. Findings suggest that these molecules may play a role in phagocytosis, chemotaxis and adherence. Profile of peripheral blood lymphocytes analyzed on a FACScan
BD Pharmingen™ Purified Mouse Anti-Human CD66b - Purified - Clone G10F5 - Isotype Mouse IgM, κ - Reactivity Hu - 0.1 mg -
Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Isotype
- IgM kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store undiluted at 4°C.
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: "Activation of human phagocytes through carbohydrate antigens (CD15, sialyl-CD15, CDw17, and CDw65)." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 10, pp. 3221-9, (1992) (PubMed).
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- CEACAM8 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8))
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Autre désignation
- CD66b
Antigène
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