CD81 anticorps

N° du produit ABIN2689415

Cet anticorps Souris Monoclonal détecte spécifiquement CD81 dans FACS. Il présente une réactivité envers Humain, Lapin et Chien et a été mentionné dans 2+ publications.

Aperçu rapide pour CD81 anticorps (ABIN2689415)

Antigène: CD81

Reactivité: Humain, Lapin, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD81 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: JS

Détail du produit anti-CD81 anticorps

Marque: BD Pharmingen™

Attributs du produit: JS-81 identifies the newly clustered CD81 antigen, a 26 kDa, type III transmembrane protein (also known as TAPA-1) that is involved in cell growth and signal transduction. CD81 has a very broad cellular distribution, being expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin. MAbs to CD81 have been shown to have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. Immunoprecipitation studies reveal that CD81 is a component of a multimolecular complex which can include the Leu13 Molecule, and the CD19 and CD21 Molecules in B cells. MAbs to CD81 are reported to induce homotypic cell aggregation. Profile of peripheral blood lymphocytes analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD81 - Purified - Clone JS-81 - Isotype Mouse IgG1, κ - Reactivity Hu, Dog, Rab - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-CD81 (ABIN2689415)

Schick, Levy: "The TAPA-1 molecule is associated on the surface of B cells with HLA-DR molecules." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 8, pp. 4090-7, (1993) (PubMed).

Oren, Takahashi, Doss, Levy, Levy: "TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins." dans: Molecular and cellular biology, Vol. 10, Issue 8, pp. 4007-15, (1990) (PubMed).

Détails sur CD81

Antigène: CD81

Autre désignation: CD81

Sujet: Synonyms: TAPA-1

Pathways: Inositol Metabolic Process, Hepatitis C