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- Antigène Voir toutes CD9 Anticorps
- CD9
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Reactivité
- Souris
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD9 est conjugé à/à la Biotin
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Application
- Flow Cytometry (FACS)
- Marque
- BD Pharmingen™
- Attributs du produit
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The KMC8 antibody reacts with CD9, a 24- kDa member of the transmembrane 4 superfamily. In the mouse, CD9 is present on bone marrow myeloid cells, stromal cells, and megakaryocyte-committed progenitors, subsets of peripheral T and B lymphocytes, and neutrophils, platelets, dendritic cells, and bone marrow-derived macrophages. CD9 has been found to be associated with integrins and other cell-surface receptors, and it is suggested to play a role in signal transduction and possibly in regulating cellular adhesive properties. It has also been demonstrated to participate in T-cell costimulation and induction of apoptosis. The KMC8 antibody has been reported to block certain CD9 functions and activate macrophages
BD Pharmingen™ Biotin Rat Anti-Mouse CD9 - Biotin - Clone KMC8 (also known as KMC 8) - Isotype Rat IgG2a, κ - Reactivity Ms - 0.1 mg - Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Immunogène
- (C57BL/6 x DBA/2)F1 mouse bone marrow-derived stromal cell line BMS2
- Clone
- KMC8
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product CD9 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
- Stock
- 4 °C
- Stockage commentaire
- Store undiluted at 4°C.
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Characterization of mouse clonogenic megakaryocyte progenitors." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 1, pp. 205-10, (2003) (PubMed).
: "Functional association of CD9 with the Fc gamma receptors in macrophages." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 5, pp. 3256-65, (2001) (PubMed).
: "CD9 molecule expressed on stromal cells is involved in osteoclastogenesis." dans: Experimental hematology, Vol. 27, Issue 5, pp. 853-9, (1999) (PubMed).
: "Differential involvement of a Fas-CPP32-like protease pathway in apoptosis of TCR/CD9-costimulated, naive T cells and TCR-restimulated, activated T cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 12, pp. 5790-6, (1998) (PubMed).
: "Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 5, pp. 2222-31, (1997) (PubMed).
: "Antibody ligation of CD9 modifies production of myeloid cells in long-term cultures." dans: Blood, Vol. 87, Issue 6, pp. 2252-61, (1996) (PubMed).
: "The ins and outs of the transmembrane 4 superfamily." dans: Immunology today, Vol. 15, Issue 12, pp. 588-94, (1995) (PubMed).
: "Platelet p24/CD9, a member of the tetraspanin family of proteins." dans: Annals of the New York Academy of Sciences, Vol. 714, pp. 175-84, (1994) (PubMed).
: "Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures." dans: The Journal of experimental medicine, Vol. 171, Issue 2, pp. 477-88, (1990) (PubMed).
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Characterization of mouse clonogenic megakaryocyte progenitors." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 1, pp. 205-10, (2003) (PubMed).
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- Antigène
- CD9
- Autre désignation
- CD9 (CD9 Produits)
- Synonymes
- anticorps BTCC-1, anticorps DRAP-27, anticorps MIC3, anticorps MRP-1, anticorps TSPAN-29, anticorps TSPAN29, anticorps Tspan29, anticorps cd9, anticorps wu:fb61g04, anticorps zgc:73383, anticorps zgc:85743, anticorps CD9 molecule, anticorps CD9 antigen, anticorps CD9 molecule a, anticorps CD9, anticorps Cd9, anticorps cd9a
- Pathways
- Response to Water Deprivation, Cell-Cell Junction Organization
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