Cité dans 2 publications.
Cet anticorps anti-Follicular Dendritic Cells Monoclonal Rat (Clone FDC) (ABIN2689507) détecte spécifiquement Follicular Dendritic Cells dans IHC (fro) et IHC (f).
L’anticorps est réactif avec des échantillons de Souris.
Follicular Dendritic Cells (FDC) form a structural network within the lymphoid follicles and are involved in antigen presentation to B cells for generating an immune response and for the maintenance of immunological memory. FDCs are believed to provide signals to B cells to induce their proliferation. In LCMV mediated immunosuppression there is evidence of T-cell dependent destruction of macrophages and follicular dendritic cells. The FDC-M1 antibody recognizes follicular dendritic cells and their dendritic processes. Immunohistochemistry of follicular dendritic cells. Frozen sections of mouse spleen was reacted with the FDC-M1 antibody. Follicular dendritic cells can be identified by the intense brown labeling of their cell membranes. Magnification 20X.
BD Pharmingen™ Purified Rat Anti-Mouse Follicular Dendritic Cell - Purified - Clone FDC-M1 - Isotype Rat IgG2c, κ - Reactivity Ms - 1 mL
Purification
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
Store undiluted at 4°C.
Kosco, Pflugfelder, Gray: "Follicular dendritic cell-dependent adhesion and proliferation of B cells in vitro." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 8, pp. 2331-9, (1992) (PubMed).
Gray, Kosco, Stockinger: "Novel pathways of antigen presentation for the maintenance of memory." dans: International immunology, Vol. 3, Issue 2, pp. 141-8, (1991) (PubMed).