MHC, Class I anticorps (Biotin)

N° du produit ABIN2689544

Cet anticorps Souris Monoclonal détecte spécifiquement MHC, Class I dans FACS, ELISA et IHC (fro). Il présente une réactivité avec des échantillons de Souris. Il a été cité dans 4+ publications.

Aperçu rapide pour MHC, Class I anticorps (Biotin) (ABIN2689544)

Antigène: MHC, Class I

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MHC, Class I est conjugé à/à la Biotin

Application: Flow Cytometry (FACS), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: SF1

Détail du produit anti-MHC, Class I anticorps (Biotin)

Attributs du produit: The SF1-1.1 antibody reacts with the α3 domain of the H-2K[d] MHC class I alloantigen. Reactivity with other haplotypes (e.g, b, j, k, p, q, s, v) has not been observed. It has been reported that plate-bound SF1-1.1 mAb moderately enhances the apoptotic response of thymocytes to plate-bound 145-2C11 mAb (anti-mouse CD3e, Cat. No. 557306/553058). This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

BD Pharmingen™ Biotin Mouse Anti-Mouse H-2K[d] - Biotin - Clone SF1-1.1 - Isotype Mouse IgG2a, κ - Reactivity Ms - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: BALB/c mouse cells

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Références pour anticorps anti-MHC, Class I (Biotin) (ABIN2689544)

Noun, Reboul, Abastado, Jaulin, Kourilsky, Pla: "Alloreactive monoclonal antibodies select Kd molecules with different peptide profiles." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 6, pp. 2455-61, (1996) (PubMed).

Zhao, Iwata: "Cross-linking of the TCR-CD3 complex with CD4, CD8 or LFA-1 induces an anti-apoptotic signal in thymocytes: the signal is canceled by FK506." dans: International immunology, Vol. 7, Issue 9, pp. 1387-96, (1996) (PubMed).

Abastado, Casrouge, Kourilsky: "Differential role of conserved and polymorphic residues of the binding groove of MHC class I molecules in the selection of peptides." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 7, pp. 3569-75, (1993) (PubMed).

Matsumoto, Setoyama, Umesaki: "Differential induction of major histocompatibility complex molecules on mouse intestine by bacterial colonization." dans: Gastroenterology, Vol. 103, Issue 6, pp. 1777-82, (1993) (PubMed).

Détails sur MHC, Class I

Antigène: MHC, Class I

Autre désignation: H-2K[d]