Humain Papilloma Virus 16 Capsid Protein (HPV-16 L1) anticorps

N° du produit ABIN2689560

Il existe 4+ publications pour ce produit. L’anticorps anti-Human Papilloma Virus 16 Capsid Protein Monoclonal Souris est utilisé pour la détection de Human Papilloma Virus 16 Capsid Protein dans des échantillons de Humain. Il a été validé pour IHC (f) et IHC (fro).

Aperçu rapide pour Humain Papilloma Virus 16 Capsid Protein (HPV-16 L1) anticorps (ABIN2689560)

Antigène: Human Papilloma Virus 16 Capsid Protein (HPV-16 L1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: CAMVIR

Détail du produit

Attributs du produit: More than 60 different types of human papilloma viruses (HPVs) have been isolated. The human papilloma viruses encode three late proteins, which are produced only in terminally differentiating keratinocytes, two of which (the L1 and L2 proteins) are structural components of the virion. Virus-like particles can be assembled by over-expressing L1 and L2 in vitro, demonstrating that L1 and L2 are necessary and sufficient components of the HPV capsomeres. HPV-16 has been reported to migrate at a reduced molecular weight of ~57 kD by SDS-PAGE. The CAMVIR-1 antibody reacts with the L1 protein of HPV-16 and may also cross-react with other HPV types, such as HPV-33. Immunohistochemistry for HPV type 16. A formalin-fixed, paraffin-embedded section from human cervix infected with HPV type 16 was stained with the Purified Mouse Anti-HPV 16 L1 antibody. Cells expressing the L1 protein of the HPV 16 virus can be identifed by the intense brown labeling (magnification 20X).

BD Pharmingen™ Purified Mouse Anti-HPV-16 L1 - Purified - Clone CAMVIR-1 - Isotype Mouse IgG2a, κ - Reactivity Hu - 1 mL

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Référence

Doorbar, Ely, Coleman, Hibma, Davies, Crawford: "Epitope-mapped monoclonal antibodies against the HPV16E1--E4 protein." dans: Virology, Vol. 187, Issue 1, pp. 353-9, (1992) (PubMed).

Zhou, Sun, Stenzel, Frazer: "Expression of vaccinia recombinant HPV 16 L1 and L2 ORF proteins in epithelial cells is sufficient for assembly of HPV virion-like particles." dans: Virology, Vol. 185, Issue 1, pp. 251-7, (1991) (PubMed).

McLean, Churcher, Meinke, Smith, Higgins, Stanley, Minson: "Production and characterisation of a monoclonal antibody to human papillomavirus type 16 using recombinant vaccinia virus." dans: Journal of clinical pathology, Vol. 43, Issue 6, pp. 488-92, (1990) (PubMed).

de Villiers: "Heterogeneity of the human papillomavirus group." dans: Journal of virology, Vol. 63, Issue 11, pp. 4898-903, (1989) (PubMed).

Détail du antigène

Antigène: Human Papilloma Virus 16 Capsid Protein (HPV-16 L1)

Autre désignation: HPV-16 L1

Classe de substances: Viral Protein