MHC Class II I-Ab anticorps
Aperçu rapide pour MHC Class II I-Ab anticorps (ABIN2689561)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Attributs du produit
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The AF6-120.1 antibody reacts with the I-A[b] MHC class II alloantigen. It cross-reacts with cells from mice of the H-2[k] and H-2[u] haplotypes. Reactivity with other haplotypes (e.g., d, f, g7, p, q, r, s) has not been observed. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.
BD Pharmingen™ Purified Mouse Anti-Mouse I-A[b] - Purified - Clone AF6-120.1 - Isotype Mouse IgG2a, κ - Reactivity Ms - 0.5 mg -
Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Immunogène
- Mouse C57BL/10J
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Isotype
- IgG2a kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store undiluted at 4°C.
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: "HLA-DQ8 transgenic mice are highly susceptible to collagen-induced arthritis: a novel model for human polyarthritis." dans: The Journal of experimental medicine, Vol. 183, Issue 1, pp. 27-37, (1996) (PubMed).
: "Identification of functional regions on the I-Ab molecule by site-directed mutagenesis." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 3, pp. 747-51, (1986) (PubMed).
: "The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex." dans: Science (New York, N.Y.), Vol. 231, Issue 4739, pp. 733-5, (1986) (PubMed).
: "Inhibition of proliferation of MIs- and Ia-reactive cloned T cells by a monoclonal antibody against a determinant shared by I-A and I-E." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 131, Issue 3, pp. 1056-64, (1983) (PubMed).
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- MHC Class II I-Ab
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Autre désignation
- I-A[b]
Antigène
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