Ly6C anticorps (Biotin)

N° du produit ABIN2689822

Cité dans 7 publications. Cet anticorps anti-Ly6C Monoclonal Rat conjugué à Biotin (Clone AL) (ABIN2689822) détecte spécifiquement Ly6C dans FACS et IHC (fro). L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour Ly6C anticorps (Biotin) (ABIN2689822)

Antigène: Ly6C (Ly-6C) (Ly-6C)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Ly6C est conjugé à/à la Biotin

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: AL

Détail du produit anti-Ly6C anticorps (Biotin)

Attributs du produit: The AL-21 antibody reacts with a non-polymorphic determinant of Ly-6C, a 14- 17- kDa GPI-linked cell-surface antigen found on some monocyte/macrophage populations, granulocytes, endothelial cells, plasma cells, and thymocyte, NK-cell, and T-subsets. Mice with the Ly-6.2 alloantigen (eg, AKR, C57BL, C57BR, C57L, C58, DBA/2, PL, SJL, SWR, 129) have subsets of CD8+ and CD4+ Ly-6C+ T cells, while Ly-6.1 strains (eg, A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+ Ly-6C+ T cells. Upregulation of Ly-6C expression on CD8+ T cells by interferons α and β and poly (I:C) has been described, and Ly-6C is a memory marker on CD8+ T cells.

BD Pharmingen™ Biotin Rat Anti-Mouse Ly-6C - Biotin - Clone AL-21 - Isotype Rat IgM, κ - Reactivity Ms - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Not reported

Isotype: IgM kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Références pour anticorps anti-Ly6C (Biotin) (ABIN2689822)

Wrammert, Källberg, Agace, Leanderson: "Ly6C expression differentiates plasma cells from other B cell subsets in mice." dans: European journal of immunology, Vol. 32, Issue 1, pp. 97-103, (2001) (PubMed).

Cerwenka, Carter, Reome, Swain, Dutton: "In vivo persistence of CD8 polarized T cell subsets producing type 1 or type 2 cytokines." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 1, pp. 97-105, (1998) (PubMed).

Sato, Yahata, Santa, Ohta, Ohmi, Habu, Nishimura: "Functional characterization of NK1.1 + Ly-6C+ cells." dans: Immunology letters, Vol. 54, Issue 1, pp. 5-9, (1997) (PubMed).

Tough, Borrow, Sprent: "Induction of bystander T cell proliferation by viruses and type I interferon in vivo." dans: Science (New York, N.Y.), Vol. 272, Issue 5270, pp. 1947-50, (1996) (PubMed).

Jutila, Kurk, Jutila: "Differences in the expression of Ly-6C on neutrophils and monocytes following PI-PLC hydrolysis and cellular activation." dans: Immunology letters, Vol. 41, Issue 1, pp. 49-57, (1994) (PubMed).

Takahama, Sharrow, Singer et al.: "Expression of an unusual T cell receptor (TCR)-V beta repertoire by Ly-6C+ subpopulations of CD4+ and/or CD8+ thymocytes. Evidence for a developmental relationship between Ly-6C+ thymocytes and ..." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 9, pp. 2883-91, (1991) (PubMed).

Jutila, Kroese, Jutila, Stall, Fiering, Herzenberg, Berg, Butcher: "Ly-6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon-gamma." dans: European journal of immunology, Vol. 18, Issue 11, pp. 1819-26, (1989) (PubMed).

Détails sur Ly6C

Antigène: Ly6C (Ly-6C) (Ly-6C)

Autre désignation: Ly-6C