VEGF anticorps

N° du produit ABIN2689962

L’anticorps Souris Monoclonal anti-VEGF a été validé pour WB, IF, IP et IHC (f). Il convient pour détecter VEGF dans des échantillons de Humain. Il y a 4+ publications disponibles.

Aperçu rapide pour VEGF anticorps (ABIN2689962)

Antigène: VEGF (Vascular Endothelial Growth Factor (VEGF))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VEGF est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: G153

Détail du produit anti-VEGF anticorps

Marque: BD Pharmingen™

Attributs du produit: Vascular endothelial growth factor (VEGF) is a heparin-binding, dimeric protein related to the PDGF/sis family of growth factors. Major sources of VEGF include pituitary cells, monocytes/macrophages, smooth muscle, and keratinocytes. VEGF is a mitogen for endothelial cells, activates and is chemoattractant for monocytes, enhances blood vessel permeability, and is a pro-coagulant. Human VEGF occurs in several molecular variants arising by alternative splicing of the mRNA. The splice forms of VEGF differ in biological properties. VEGF is a homodimeric heavily glycosylated protein of 46-48 kDa (18-25 kDa subunits). Glycosylation is not required, however, for biological activity. The subunits are linked by disulphide bonds. Different isoforms of VEGF have different properties in vitro and this may apply also to their in vivo functions. VEGF Immonohistochemical staining on human colon tissue.

BD Pharmingen™ Purified Mouse Anti-Human VEGF - Purified - Clone G153-694 - Isotype Mouse IgG2b, κ - Reactivity Hu - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-VEGF (ABIN2689962)

Andersson, Abrams, Björk, Funa, Litton, Agren, Andersson: "Concomitant in vivo production of 19 different cytokines in human tonsils." dans: Immunology, Vol. 83, Issue 1, pp. 16-24, (1995) (PubMed).

Norrby-Teglund, Norgren, Holm, Andersson, Andersson: "Similar cytokine induction profiles of a novel streptococcal exotoxin, MF, and pyrogenic exotoxins A and B." dans: Infection and immunity, Vol. 62, Issue 9, pp. 3731-8, (1994) (PubMed).

Fernandez, Andersson, Andersson, Troye-Blomberg: "Cytokine synthesis analyzed at the single-cell level before and after revaccination with tetanus toxoid." dans: European journal of immunology, Vol. 24, Issue 8, pp. 1808-15, (1994) (PubMed).

Skansén-Saphir, Andersson, Björk, Andersson: "Lymphokine production induced by streptococcal pyrogenic exotoxin-A is selectively down-regulated by pooled human IgG." dans: European journal of immunology, Vol. 24, Issue 4, pp. 916-22, (1994) (PubMed).

Détails sur VEGF

Antigène: VEGF (Vascular Endothelial Growth Factor (VEGF))

Autre désignation: VEGF