pan Keratin anticorps (AA 331-430) (AbBy Fluor® 350)

N° du produit ABIN2690210

L’anticorps Lapin Polyclonal anti-pan Keratin a été validé pour IF (cc) et IF (p). Il convient pour détecter pan Keratin dans des échantillons de Humain et Rat.

Aperçu rapide pour pan Keratin anticorps (AA 331-430) (AbBy Fluor® 350) (ABIN2690210)

Antigène: pan Keratin (panKRT)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp pan Keratin est conjugé à/à la AbBy Fluor® 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-pan Keratin anticorps (AbBy Fluor® 350)

Épitope: AA 331-430

Specificité: This will target: CK4, CK75, CK3, CK2, CK6C, CK6A, keratin 6E

Réactivité croisée: Humain, Rat

Homologie: Mouse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CK5

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur pan Keratin

Antigène: pan Keratin (panKRT)

Autre désignation: Keratin

Sujet:

Synonyms: CK4, CK75, CK3, CK2, CK6C, CK6A, keratin 6E, P-CK

Background: Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinising tissue (ie., skin) and non keratinising cells (ie., mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40 to 70 kDa and isoelectric points of 5 to 8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Defects in KRT5 are a cause of epidermolysis bullosa simplex.