BCAT1 anticorps

N° du produit ABIN2716546

Il existe 2+ publications pour ce produit. L’anticorps anti-BCAT1 Monoclonal Souris est utilisé pour la détection de BCAT1 dans des échantillons de Humain, Souris et Chien. Il a été validé pour WB et IHC.

Aperçu rapide pour BCAT1 anticorps (ABIN2716546)

Antigène: BCAT1 (Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1))

Reactivité: Humain, Souris, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BCAT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 3F5

Détail du produit anti-BCAT1 anticorps

Attributs du produit: Homo sapiens branched chain amino-acid transaminase 1, cytosolic (BCAT1), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human BCAT1(NP_005495) produced in HEK293T cell.

Isotype: IgG2a

Information d'application

Indications d'application: WB 1:500~2000, IHC 1:150,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-BCAT1 (ABIN2716546)

Cho, Jeon, Park, Park, Kang, Choi: "BCAT1 is a New MR Imaging-related Biomarker for Prognosis Prediction in IDH1-wildtype Glioblastoma Patients." dans: Scientific reports, Vol. 7, Issue 1, pp. 17740, (2017) (PubMed).

Hattori, Tsunoda, Konuma, Kobayashi, Nagy, Glushka, Tayyari, McSkimming, Kannan, Tojo, Edison, Ito: "Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia." dans: Nature, Vol. 545, Issue 7655, pp. 500-504, (2017) (PubMed).

Détails sur BCAT1

Antigène: BCAT1 (Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1))

Autre désignation: BCAT1

Sujet: This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.

Poids moléculaire: 42.8 kDa

ID gène: 586

NCBI Accession: NM_005504

HGNC: 586