N-Cadherin anticorps

N° du produit ABIN2716943

Cet anticorps anti-N-Cadherin est un anticorps Souris Monoclonal détectant N-Cadherin dans WB, IHC et FACS. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour N-Cadherin anticorps (ABIN2716943)

Antigène: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp N-Cadherin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 3B10

Détail du produit anti-N-Cadherin anticorps

Attributs du produit: Homo sapiens cadherin 2, type 1, N-cadherin (neuronal) (CDH2)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human CDH2(NP_001783) produced in HEK293T cell.

Isotype: IgG2a

Information d'application

Indications d'application: WB 1:2000, IHC 1:150, FLOW 1:100,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-N-Cadherin (ABIN2716943)

Zhang, He, Chen, Pan, Du, Zang, Wang, Tang, Li, Lu, Yao, Jin, Ma: "Chemotherapy enhances tumor vascularization via Notch signaling-mediated formation of tumor-derived endothelium in breast cancer." dans: Biochemical pharmacology, Vol. 118, pp. 18-30, (2016) (PubMed).

Détails sur N-Cadherin

Antigène: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Autre désignation: CDH2

Sujet: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

Poids moléculaire: 97.2 kDa

ID gène: 1000

NCBI Accession: NM_001792

HGNC: 1000

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane