Catalase anticorps

N° du produit ABIN2717106

L’anticorps Souris Monoclonal anti-Catalase a été validé pour WB, IHC et IF. Il convient pour détecter Catalase dans des échantillons de Humain, Rat, Chien et Singe. Il y a 1 publication disponible.

Aperçu rapide pour Catalase anticorps (ABIN2717106)

Antigène: Catalase (CAT)

Reactivité: Humain, Rat, Chien, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Catalase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 1B6

Détail du produit anti-Catalase anticorps

Attributs du produit: Homo sapiens catalase (CAT)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human CAT (NP_111743) produced in HEK293T cell.

Isotype: IgG1

Information d'application

Indications d'application: WB 1:200~500, IHC 1:150, IF 1:100,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-Catalase (ABIN2717106)

Benlloch, Obrador, Valles, Rodriguez, Sirerol, Alcácer, Pellicer, Salvador, Cerdá, Sáez, Estrela: "Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism." dans: Antioxidants & redox signaling, Vol. 24, Issue 17, pp. 974-90, (2016) (PubMed).

Détails sur Catalase

Antigène: Catalase (CAT)

Autre désignation: CAT

Sujet: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.

Poids moléculaire: 59.6 kDa

ID gène: 847

NCBI Accession: NM_001752

HGNC: 847

Pathways: Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism