Peripherin anticorps

N° du produit ABIN271783

Cet anticorps Lapin Polyclonal détecte spécifiquement Peripherin dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour Peripherin anticorps (ABIN271783)

Antigène: Peripherin (PRPH)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Peripherin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Peripherin anticorps

Specificité: This antibody detects endogenous levels of Peripherin protein. (region surrounding Ser454)

Réactivité croisée (Details): Species reactivity (tested):Human, Rat.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Peripherin

Antigène: Peripherin (PRPH)

Autre désignation: Peripherin

Sujet: Peripherin is a type III intermediate filament protein that is expressed in peripheral and some central nervous system (CNS) neurons. Peripherin activation is known to be induced by leukemia inhibitory factor (LIF). LIF activates Peripherin by inducing members of STAT transcription factor family to bind to a specific promoter element in the Peripherin gene. IL-6 is also known to induce Peripherin expression. Although it is not essential for neurite formation, peripherin is necessary for cellular intermediate filament network formation. Peripherin, unlike most intermediate filament proteins, has been reported to be modified by tyrosine phosphorylation.Synonyms: NEF4, PRPH, PRPH1

Poids moléculaire: approx. 55 kDa

ID gène: 5630

NCBI Accession: NP_006253

UniProt: P41219