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POLR2A/RPB1 anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement POLR2A/RPB1 dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain, Souris et Rat.
N° du produit ABIN271906

Aperçu rapide pour POLR2A/RPB1 anticorps (ABIN271906)

Antigène

Voir toutes POLR2A/RPB1 (POLR2A) Anticorps
POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

Reactivité

  • 88
  • 40
  • 39
  • 6
  • 6
  • 6
  • 5
  • 5
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 70
  • 18
  • 1
  • 1
  • 1
Lapin

Clonalité

  • 49
  • 42
Polyclonal

Conjugué

  • 60
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
Cet anticorp POLR2A/RPB1 est non-conjugé

Application

  • 54
  • 33
  • 28
  • 28
  • 17
  • 10
  • 10
  • 8
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Specificité

    This antibody detects endogenous levels of POLR2A protein. (region surrounding Pro1613)

    Réactivité croisée (Details)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    Purification

    Affinity Chromatography using epitope-specific immunogen.
  • Indications d'application

    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

    Autre désignation

    POLR2A

    Sujet

    RPB1 is a subunit of RNA polymerase II which catalyses transcription of RNA from DNA. RPB1 forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template.Synonyms: DNA-directed RNA polymerase II largest subunit, DNA-directed RNA polymerase II subunit RPB1, POLR2, POLRA, RNA polymerase II, RNA polymerase II 220 kd, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RPB1, RPB220, RPOL2

    Poids moléculaire

    217,240 kDa

    ID gène

    5430

    NCBI Accession

    NP_000928

    UniProt

    P24928

    Pathways

    Regulatory RNA Pathways
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