DAND5 anticorps (AA 23-189)

N° du produit ABIN2719202

L’anticorps Souris Monoclonal anti-DAND5 a été validé pour WB, IHC et FACS. Il convient pour détecter DAND5 dans des échantillons de Humain.

Aperçu rapide pour DAND5 anticorps (AA 23-189) (ABIN2719202)

Antigène: DAND5 (DAN Domain Family, Member 5 (DAND5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DAND5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 2H3

Détail du produit anti-DAND5 anticorps

Épitope: AA 23-189

Attributs du produit: Homo sapiens DAN domain family, member 5 (DAND5)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Human recombinant protein fragment corresponding to amino acids 23-189 of human DAND5(NP_689867) produced in E.coli.

Isotype: IgG1

Information d'application

Indications d'application: WB 1:500~2000, IHC 1:150, FLOW 1:100,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur DAND5

Antigène: DAND5 (DAN Domain Family, Member 5 (DAND5))

Autre désignation: DAND5

Sujet: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.

Poids moléculaire: 18 kDa

ID gène: 199699

NCBI Accession: NM_152654

HGNC: 199699