UBR5 anticorps

N° du produit ABIN271946

L’anticorps anti-UBR5 Polyclonal Lapin est utilisé pour la détection de UBR5 dans des échantillons de Humain et Souris. Il a été validé pour WB et IHC (p).

Aperçu rapide pour UBR5 anticorps (ABIN271946)

Antigène: UBR5 (Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBR5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-UBR5 anticorps

Specificité: This antibody detects endogenous levels of EDD protein. (region surrounding Thr14)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur UBR5

Antigène: UBR5 (Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5))

Autre désignation: UBR5 / HYD

Sujet: EDD (for E3 identified by Differential Display) is a progestin-regulated gene that was isolated from T-47D human breast cancer cells. Based on sequence homology, EDD appears to be a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor gene that is required for control of imaginal disc growth (2). EDD contains a HECT domain in the carboxy terminus. HECT domain-containing proteins function as ubiquitin-protein ligases, or E3 enzymes. EDD has been shown to bind to ubiquitin, and like other HECT family proteins, may function as an E3 ubiquitin-protein ligase.Synonyms: E3 ubiquitin-protein ligase, E3 ubiquitin-protein ligase UBR5, EDD, EDD1, HECT domain-containing 1, Hyperplastic discs protein homolog, KIAA0896

Poids moléculaire: approx. 309 kDa

ID gène: 51366

NCBI Accession: NP_056986

UniProt: O95071

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway