NUB1 anticorps

N° du produit ABIN271950

Cet anticorps anti-NUB1 Polyclonal Lapin (ABIN271950) détecte spécifiquement NUB1 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour NUB1 anticorps (ABIN271950)

Antigène: NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-NUB1 anticorps

Specificité: This antibody detects endogenous levels of NUB1 protein. (region surrounding Tyr601)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur NUB1

Antigène: NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))

Autre désignation: NUB1

Sujet: NUB1 is a ubiquitin-like protein that controls vital biological events through its conjugation to cullin proteins. NUB1 is a negative regulator of the NEDD8 system that recruits NEDD8 and its conjugates to the proteasome for degradation. It is, therefore a cell growth regulator. The UBA domain of NUB1 is the specific acceptor for the linear ubiquitin precursor. NUB1 is composed of 601 amino acids. It is an interferon-inducible protein and predominantly localizes in the nucleus. NUB1 is specifically expressed in adult human testis, ovary, heart, and skeletal muscle tissues.Synonyms: NEDD8 μLtimate buster 1, NYREN18, Negative regulator of ubiquitin-like proteins 1, Renal carcinoma antigen NY-REN-18

Poids moléculaire: approx. 70 kDa

ID gène: 51667

NCBI Accession: NP_057202

UniProt: Q9Y5A7