MMP10 anticorps

N° du produit ABIN272036

L’anticorps anti-MMP10 Polyclonal Lapin est utilisé pour la détection de MMP10 dans des échantillons de Humain, Souris et Rat. Il a été validé pour IF et IHC (p).

Aperçu rapide pour MMP10 anticorps (ABIN272036)

Antigène: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP10 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MMP10 anticorps

Specificité: This antibody detects endogenous levels of MMP-10 protein. (region surrounding Ile387)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MMP10

Antigène: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Autre désignation: MMP-10

Sujet: Proteins of the matrix metalloproteinase (MMP) family are zinc containing proteolytic enzymes involved in the breakdown of the extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling. They also play an important role in apoptosis, tumor cell growth, invasion, metastasis, as well as in angiogenesis and wound healing. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. Most of the MMP's contain a common domain structure, which include a signal sequence, a propeptide, a catalytic domain and a hemopexin-like (Hpx) domain. MMP10 degrades proteoglycans, gelatins of type I, III, IV, and V, weakly collagens III, IV, and V. and fibronectin. It activates procollagenase. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.Synonyms: MMP10, Matrix metalloproteinase-10, SL-2, STMY2, Stromelysin-2, Transin-2

Poids moléculaire: approx. 54 kDa

ID gène: 4319

NCBI Accession: NP_002416

UniProt: P09238