MST1 anticorps

N° du produit ABIN272039

L’anticorps anti-MST1 Polyclonal Lapin est utilisé pour la détection de MST1 dans des échantillons de Humain et Souris. Il a été validé pour WB et IHC (p).

Aperçu rapide pour MST1 anticorps (ABIN272039)

Antigène: MST1 (Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) (MST1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MST1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MST1 anticorps

Specificité: This antibody detects endogenous levels of MST1/2 protein. (region surrounding Meth178)

Réactivité croisée (Details): Species reactivity (tested):Human and Mouse.
Also reacts to: MST2

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur MST1

Antigène: MST1 (Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) (MST1))

Autre désignation: Macrophage Stimulatory Protein

Sujet: Sterile-20 (STE20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein coupled receptors to cytosolic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to STE20 are divided into two groups, the PAK subfamily and the GCK subfamily. The PAK subfamily members contain a C-terminal catalytic domain and an N-terminal regulatory domain with a p21Rac/Cdc42-binding site, and these kinases can activate both p38MAPK and JNK. The GCK subfamily members contain a C-terminal regulatory domain and an Nterminal catalytic domain, and they have diverse roles in many pathways, including the activation of ERK< JNK, p38 MAPK, and caspase-3. The mammalian STE20-like kinases (MST kinases, also known as Ksr proteins) are members of the GCK subfamily.Synonyms: D3F15S2, DNF15S2, HGFL, Hepatocyte growth factor-like protein, Hepatocyte growth factor-like protein alpha chain, Hepatocyte growth factor-like protein beta chain, MSP, MST1, Macrophage-stimulating protein

Poids moléculaire: approx. 65 kDa

ID gène: 4485

NCBI Accession: NP_066278

UniProt: P26927