FMR1 anticorps (AA 36-279)

N° du produit ABIN2721254

Cet anticorps anti-FMR1 Monoclonal Souris (Clone 1D10) (ABIN2721254) détecte spécifiquement FMR1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien et Singe.

Aperçu rapide pour FMR1 anticorps (AA 36-279) (ABIN2721254)

Antigène: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Reactivité: Humain, Souris, Rat, Chien, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FMR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 1D10

Détail du produit anti-FMR1 anticorps

Épitope: AA 36-279

Attributs du produit: Homo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Human recombinant protein fragment corresponding to amino acids 36-279 of human FMR1(NP_002015) produced in E.coli.

Isotype: IgG2b

Information d'application

Indications d'application: WB 1:500~2000, IHC 1:50,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur FMR1

Antigène: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Autre désignation: FMR1

Sujet: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Poids moléculaire: 71 kDa

ID gène: 2332

NCBI Accession: NM_002024

HGNC: 2332

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development