IRF2 anticorps

N° du produit ABIN272167

Détail du produit anti-IRF2 anticorps

Antigène: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of IRF-2 protein. (region surrounding Lys129)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IRF2

Antigène: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Autre désignation: IRF2 (IRF2 Produits)

Synonymes: anticorps IRF-2, anticorps 9830146E22Rik, anticorps AI646973, anticorps Irf-2, anticorps irf2b, anticorps zgc:103451, anticorps irf-2, anticorps wu:fc74h04, anticorps zgc:76951, anticorps interferon regulatory factor 2, anticorps interferon regulatory factor 2 L homeolog, anticorps interferon regulatory factor 2a, anticorps IRF2, anticorps Irf2, anticorps irf2, anticorps irf2.L, anticorps irf2a

Sujet: Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-alpha and beta) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-alpha and interferon-beta genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth, overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3gamma p48 (the 48 kDa component of the ISGF-3 complex) and IFN consensus sequence-binding protein (ICSBP).Synonyms: IRF-2, Interferon regulatory factor 2

Poids moléculaire: approx. 47 kDa

ID gène: 3660

NCBI Accession: NP_002190

UniProt: P14316