CEBPB anticorps

N° du produit ABIN272175

Détail du produit anti-CEBPB anticorps

Antigène: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEBPB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of C/EBP-β protein. (region surrounding Val259)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity Purified

Information d'application

Indications d'application: ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CEBPB

Antigène: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Autre désignation: CEBPB (CEBPB Produits)

Synonymes: anticorps C/EBPbeta, anticorps c/ebp-beta, anticorps crp2, anticorps il6dbp, anticorps lap, anticorps nf-il6, anticorps tcf5, anticorps xC/EBPbeta, anticorps cebpbb, anticorps cb380, anticorps c/ebpb, anticorps fe11e05, anticorps wu:fe11e05, anticorps CEBPB, anticorps LOC100136165, anticorps C/EBP-beta, anticorps CRP2, anticorps IL6DBP, anticorps LAP, anticorps NF-IL6, anticorps TCF5, anticorps IL-6DBP, anticorps LIP, anticorps NF-M, anticorps Nfil6, anticorps Il6dbp, anticorps CCAAT/enhancer binding protein beta, anticorps CCAAT/enhancer binding protein beta L homeolog, anticorps CCAAT/enhancer binding protein (C/EBP), beta, anticorps CCAAT/enhancer-binding protein beta, anticorps cebpb, anticorps cebpb.L, anticorps CEBPB, anticorps LOC100136165, anticorps Cebpb

Sujet: C/EBP β is a member of the C/EBP transcription factor family. The C/EBP β gene encodes several isoforms, which have truncated transcription activation domains by the alternative translational initiation at multipe AUG start sites. Initiation of translation at the in-frame AUGs forms four C/EBP β isoforms. C/EBP β is also known as interleukin 6-dependent DNA-binding protein (IL6DBP), liver activator protein(LAP) or liver-enriched transcriptional activator protein transcription factor 5 (TCF5). C/EBP β contributes to the regulation of the acute phase response in hepatocytes. Stat3 has an important function in IL-6-mediated transcription of the C/EBP β gene that has direct implication for acute phase response in liver cells.The 35 kDa C/EBP β form requires phosphorylation for its DNA binding ability, and increased binding of C/EBP β isoforms during acute-phase reaction occurs through its upregulation and structural modification.Synonyms: C/EBP beta, CCAAT/enhancer-binding protein beta, LAP, Liver activator protein, NF-IL6, Nuclear factor NF-IL6, TCF5, Transcription factor 5

Poids moléculaire: approx. 36 kDa

ID gène: 1051

NCBI Accession: NP_005185

UniProt: P17676

Pathways: Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation