NCBP2 anticorps

N° du produit ABIN272203

Détail du produit anti-NCBP2 anticorps

Antigène: NCBP2 (Nuclear Cap Binding Protein Subunit 2 (NCBP2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCBP2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of CBP20 protein. (region surrounding Arg21)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur NCBP2

Antigène: NCBP2 (Nuclear Cap Binding Protein Subunit 2 (NCBP2))

Autre désignation: NCBP2 (NCBP2 Produits)

Synonymes: anticorps CBP20, anticorps CG12357, anticorps Dmel\\CG12357, anticorps 20kDa, anticorps 5930413E18Rik, anticorps AA536802, anticorps AI843301, anticorps C79367, anticorps CHUNP6917, anticorps zgc:92592, anticorps CBC2, anticorps NIP1, anticorps ATCBP20, anticorps CAP-binding protein 20, anticorps MLN1.12, anticorps MLN1_12, anticorps Ncbp2, anticorps cap binding protein 20, anticorps nuclear cap binding protein subunit 2, anticorps nuclear cap binding protein subunit 2, 20kDa, anticorps nuclear cap binding protein subunit 2 L homeolog, anticorps nuclear cap-binding protein subunit 2, anticorps CAP-binding protein 20, anticorps Nuclear cap-binding protein subunit 2, anticorps Cbp20, anticorps Ncbp2, anticorps ncbp2, anticorps NCBP2, anticorps ncbp2.L, anticorps CBP20, anticorps ncbp-2

Sujet: In eukaryotes, the majority of mRNAs have an m(7)G cap, which is added cotranscriptionally and plays a critical role in many aspects of mRNA metabolism. The effect of the cap on translation is mediated by the initiation factor eIF-4F, whereas the effect on pre-mRNA splicing involves a nuclear complex (CBC). CBC consists of two cap binding proteins, CBP20 and CBP80, which mediate the stimulatory functions of the cap in pre-mRNA splicing, 3' end formation and U snRNA export. The genes CBC1 and CBC2 encode CBP80 and CBP20, respectively. CBP80 comprises three domains, each containing a MIF4G domain. CBP20 has an RNAP fold and associates with the second and third domains of CBP80. CBP also plays a role in nonsense-mediated decay (NMD), a process which eliminates mRNAs, and prematurely terminates translation. CBP80-bound mRNA undergoes a pioneer round of translation before CBP80-CBP20 are replaced by eIF4E, and Upf2 and Upf3 proteins.Synonyms: CBP20, Nuclear cap-binding protein subunit 2, PIG55

Poids moléculaire: approx. 18 kDa

ID gène: 22916

NCBI Accession: NP_001036005

UniProt: P52298

Pathways: Ribonucleoprotein Complex Subunit Organization, Methionine Biosynthetic Process