LTA anticorps
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- Antigène Voir toutes LTA Anticorps
- LTA (Lymphotoxin-alpha (LTA))
- Reactivité
- Veuillez nous consulter SVP
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LTA est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects endogenous levels of LT-beta protein. (region surrounding Val211)
- Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Pureté
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product LTA Anticorps primaire
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- Indications d'application
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- DO NOT FREEZE!
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- LTA (Lymphotoxin-alpha (LTA))
- Autre désignation
- TNF-beta / Lymphotoxin-alpha (LTA Produits)
- Synonymes
- anticorps LT, anticorps TNFB, anticorps TNFSF1, anticorps LT-[a], anticorps LT-alpha, anticorps LT[a], anticorps LTalpha, anticorps Ltx, anticorps TNF-beta, anticorps Tnfb, anticorps Tnfsf1b, anticorps hlb382, anticorps lymphotoxin alpha, anticorps lymphotoxin A, anticorps LTA, anticorps Lta
- Classe de substances
- Chemical
- Sujet
- Tumor necrosis factor (TNF) and lymphotoxin-alpha (LT-alpha, also known as TNF-beta) are members of a family of secreted and cell surface cytokines that participate in the regulation of immune and inflammatory responses. LT-beta (lymphotaxin-beta or tumor necrosis factor C) is a type II membrane protein with significant homology to TNF, LT-alpha, and the ligand for the CD40 receptor. LT-alpha is present on the surface of activated T, B, and LAK cells as a complex with the 33 kda glycoprotein, LT-beta. LT-beta, also expressed by active lymphocytes, forms a heterotrimer with LT-a on the cell surface and anchors LT-alpha to the cell surface. A TNF receptor-related protein, the LT-beta receptor (also known as TNFC receptor), is the human receptor for the LT-alpha/LT-beta heterotrimer. There are two LT-beta isoforms expressed in human lymphoid cell lines and non-Hodgkin's lymphomas. The gene which encodes LT-beta maps to the major histocompatibility complex region on human chromosome 6p21.3.Synonyms: LT-alpha, LTA, TNFB, TNFSF1, Tumor necrosis factor ligand superfamily member 1
- Poids moléculaire
- approx. 22 kDa
- ID gène
- 4049
- NCBI Accession
- NP_000586
- UniProt
- P01374
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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