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NFIA anticorps

NFIA Reactivité: Humain, Souris, Rat WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN272219
  • Antigène Voir toutes NFIA Anticorps
    NFIA (Nuclear Factor I/A (NFIA))
    Reactivité
    • 49
    • 19
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Humain, Souris, Rat
    Hôte
    • 43
    • 6
    Lapin
    Clonalité
    • 43
    • 6
    Polyclonal
    Conjugué
    • 32
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NFIA est non-conjugé
    Application
    • 42
    • 18
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects endogenous levels of NF-1 protein. (region surrounding Gln34)
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    Pureté
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product NFIA Anticorps primaire
  • Indications d'application
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    DO NOT FREEZE!
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    NFIA (Nuclear Factor I/A (NFIA))
    Autre désignation
    NFIA (NFIA Produits)
    Synonymes
    anticorps NFIA, anticorps CTF, anticorps NF-I/A, anticorps NF1-A, anticorps NFI-A, anticorps NFI-L, anticorps si:ch211-88d2.2, anticorps wu:fq27e07, anticorps zgc:158351, anticorps CNFI-A, anticorps cNFI-A3, anticorps 1110047K16Rik, anticorps 9430022M17Rik, anticorps NF1A, anticorps nuclear factor I A, anticorps nuclear factor I/A, anticorps NFIA, anticorps nfia, anticorps Nfia
    Sujet
    NF-1, also designated CTF, consists of a family of CCAAT-box-binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA-binding domain, and activates transcription through a putatively novel, proline-rich, carboxy-terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, α-globin, HSP 70, GRP 78, Histone H1,myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.Synonyms: CCAAT-box-binding transcription factor, CTG, NF-I/A, NFI-A, Nuclear factor 1 A-type, TGGCA-binding protein
    Poids moléculaire
    approx. 55 kDa
    ID gène
    4774
    NCBI Accession
    NP_001128145
    UniProt
    Q12857
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