DGKD anticorps
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- Antigène Voir toutes DGKD Anticorps
- DGKD (Diacylglycerol Kinase, delta 130kDa (DGKD))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DGKD est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of DGK-δ protein. (region surrounding Ser66)
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Pureté
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product DGKD Anticorps primaire
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- Indications d'application
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- DGKD (Diacylglycerol Kinase, delta 130kDa (DGKD))
- Autre désignation
- DAG Kinase delta (DGKD Produits)
- Synonymes
- anticorps RGD1563309, anticorps AI841987, anticorps D330025K09, anticorps DGKdelta, anticorps dgkd-2, anticorps diacylglycerol kinase, delta, anticorps diacylglycerol kinase delta, anticorps diacylglycerol kinase kappa, anticorps Dgkd, anticorps DGKD, anticorps dgkd, anticorps DGKK
- Sujet
- Diacylglycerol kinases (DGKs) phosphorylate diacylglycerol (DAG) to produce phosphatidic acid. DAG and phosphatidic acid are lipids that act as second messengers in signaling cascades. DGK-α influences cell activation and secretion of lethal exosomes, which in turn control cell death. DGK-β is abundant in restricted brain regions such as the caudate putamen and olfactory tubercle. DGK-γ encodes full-length and truncated transcripts that are present in a range of human tissues, with greatest expression observed in retina. DGK-δ is most abundant in skeletal muscle. DGK-ε shows specificity for arachidonylcontaining diacylglycerol and is expressed predominantly in testis. DGK-θ is most abundant in the cerebellum and hippocampus. DGK-ι is present in brain and retina as a predominant transcript of more than 12 kb, including a long 3-prime untranslated region, with additional low abundance transcripts of 9.5 and 7.5 kb. DGK-η is closely related to DGK-δ. DGK-ζ is most abundant in brain and muscle. DGKs have structural motifs that play regulatory roles, and these motifs form the basis for dividing the DGKs into five subtypes.Synonyms: DGK-delta, DGKD, Diacylglycerol kinase delta, Diglyceride kinase delta, KIAA0145
- Poids moléculaire
- approx. 135 kDa
- ID gène
- 8527
- NCBI Accession
- NP_003639
- UniProt
- Q16760
- Pathways
- EGFR Signaling Pathway
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