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DGKD anticorps

DGKD Reactivité: Humain WB, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN272240
  • Antigène Voir toutes DGKD Anticorps
    DGKD (Diacylglycerol Kinase, delta 130kDa (DGKD))
    Reactivité
    • 31
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 31
    Lapin
    Clonalité
    • 31
    Polyclonal
    Conjugué
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DGKD est non-conjugé
    Application
    • 24
    • 15
    • 14
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    This antibody detects endogenous levels of DGK-δ protein. (region surrounding Ser66)
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    Pureté
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product DGKD Anticorps primaire
  • Indications d'application
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    DGKD (Diacylglycerol Kinase, delta 130kDa (DGKD))
    Autre désignation
    DAG Kinase delta (DGKD Produits)
    Synonymes
    anticorps RGD1563309, anticorps AI841987, anticorps D330025K09, anticorps DGKdelta, anticorps dgkd-2, anticorps diacylglycerol kinase, delta, anticorps diacylglycerol kinase delta, anticorps diacylglycerol kinase kappa, anticorps Dgkd, anticorps DGKD, anticorps dgkd, anticorps DGKK
    Sujet
    Diacylglycerol kinases (DGKs) phosphorylate diacylglycerol (DAG) to produce phosphatidic acid. DAG and phosphatidic acid are lipids that act as second messengers in signaling cascades. DGK-α influences cell activation and secretion of lethal exosomes, which in turn control cell death. DGK-β is abundant in restricted brain regions such as the caudate putamen and olfactory tubercle. DGK-γ encodes full-length and truncated transcripts that are present in a range of human tissues, with greatest expression observed in retina. DGK-δ is most abundant in skeletal muscle. DGK-ε shows specificity for arachidonylcontaining diacylglycerol and is expressed predominantly in testis. DGK-θ is most abundant in the cerebellum and hippocampus. DGK-ι is present in brain and retina as a predominant transcript of more than 12 kb, including a long 3-prime untranslated region, with additional low abundance transcripts of 9.5 and 7.5 kb. DGK-η is closely related to DGK-δ. DGK-ζ is most abundant in brain and muscle. DGKs have structural motifs that play regulatory roles, and these motifs form the basis for dividing the DGKs into five subtypes.Synonyms: DGK-delta, DGKD, Diacylglycerol kinase delta, Diglyceride kinase delta, KIAA0145
    Poids moléculaire
    approx. 135 kDa
    ID gène
    8527
    NCBI Accession
    NP_003639
    UniProt
    Q16760
    Pathways
    EGFR Signaling Pathway
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