Septin 1 anticorps

N° du produit ABIN272245

Détail du produit anti-Septin 1 anticorps

Antigène: Septin 1 (SEPT1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Septin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Septin 1 protein. (region surrounding Asp205)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur Septin 1

Antigène: Septin 1 (SEPT1)

Autre désignation: Septin-1 (SEPT1) (SEPT1 Produits)

Synonymes: anticorps DIFF6, anticorps LARP, anticorps PNUTL3, anticorps SEP1, anticorps CG1403, anticorps Diff6, anticorps Dmel\\CG1403, anticorps anon-19Fa, anticorps iby, anticorps sep1, anticorps tu1, anticorps Pnutl3, anticorps SEPT1, anticorps Septin-1, anticorps septin 1, anticorps Septin 1, anticorps pfam02452; PemK, anticorps SEPT1, anticorps Sep1, anticorps Sept1, anticorps sepT1

Sujet: The septins are a family of GTPase enzymes, some of which are required for cytokinesis and others of which are associated with exocytosis. Members of the septin family can form heteropolymer complexes and also play a role in the organization of new growth in organisms. The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. At least three septins (Septin 1, 2 and 4) are associated with a Tau-based paired helical filament core and may contribute to the formation of neurofibrillary tangle as integral constituents of paired helical filaments. Septin 3 (G-Septin), a GTP-binding protein, is highly expressed in brain and is regulated by protein kinase G in neurons. The human SEPT4 (H5/PNUTL2/CDCrREL-2) gene encodes ARTS (for apoptosis-related protein in the TGFβ signaling pathway), which is expressed in many cells and acts to enhance cell death induced by TGFβ or, to a lesser extent, by other apoptotic agents. ARTS is localized to mitochondria and translocates to the nucleus when apoptosis occurs.Synonyms: DIFF6, LARP, NY-BR-24, PNUTL3, Peanut-like protein 3, Serologically defined breast cancer antigen NY-BR-24

Poids moléculaire: approx. 40 kDa

ID gène: 1731

NCBI Accession: NP_443070

UniProt: Q8WYJ6