HOXA7 anticorps

N° du produit ABIN272304

Cet anticorps anti-HOXA7 est un anticorps Lapin Polyclonal détectant HOXA7 dans WB et EIA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour HOXA7 anticorps (ABIN272304)

Antigène: HOXA7 (Homeobox A7 (HOXA7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOXA7 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-HOXA7 anticorps

Specificité: This antibody detects endogenous levels of Hox-A7 protein. (region surrounding Gly127)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur HOXA7

Antigène: HOXA7 (Homeobox A7 (HOXA7))

Autre désignation: HOXA7 / HOX1A

Sujet: Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxA1 is transcriptionally regulated by retinoic acid (RA) and encodes a transcription factor which has been shown to play important roles in cell differentiation and embryogenesis. HoxA1 is also expressed in cancers, such as mammary tumors, though it is not expressed in normal gland or in precancerous mammary tissues. At embryonic stages, HoxA2 is expressed in the mesenchyme and epithelial cells of the palate, however its expression is restricted to the tips of the growing palatal shelves. HoxA2 protein is predominantly expressed in the nuclei of cells in the ventral mantle region of the developing embryo. In the developing and adult mouse spinal cord, HoxA2 protein may contribute to dorsal-ventral patterning and/or to the specification of neuronal phenotype. HoxA7 functions as a potent transcriptional repressor and its action as such requires several domains, including both activator and repressor regions. HoxA7 is expressed in the fetal liver, lung, skeletal muscle, kidney, pancreas and placenta.Synonyms: Homeobox protein Hox-A7, Hox-1A

Poids moléculaire: approx. 25 kDa

ID gène: 3204

NCBI Accession: NP_008827

UniProt: P31268