HSPB8 anticorps

N° du produit ABIN2723116

Cet anticorps Souris Monoclonal détecte spécifiquement HSPB8 dans WB, IF et FACS. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour HSPB8 anticorps (ABIN2723116)

Antigène: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HSPB8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 1E3

Détail du produit anti-HSPB8 anticorps

Attributs du produit: Homo sapiens heat shock 22 kDa protein 8 (HSPB8)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human HSPB8(NP_055180) produced in HEK293T cell.

Isotype: IgG2a

Information d'application

Indications d'application: WB 1:500~2000, IF 1:100, FLOW 1:100

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur HSPB8

Antigène: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Autre désignation: HSPB8

Sujet: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Poids moléculaire: 21.4 kDa

ID gène: 26353

NCBI Accession: NM_014365

HGNC: 26353