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TNNI3 anticorps
TNNI3
Reactivité: Humain, Souris, Boeuf (Vache), Lapin, Poisson, Poulet, Amphibien
WB, EIA
Hôte: Souris
Monoclonal
C5
unconjugated
Détail du produit anti-TNNI3 anticorps
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Antigène
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TNNI3
(Cardiac Troponin I (TNNI3))
Reactivité
Toutes les réactivités sur TNNI3 Anticorps
Humain, Souris, Boeuf (Vache), Lapin, Poisson, Poulet, Amphibien
Hôte
Toutes les hôtes sur TNNI3 Anticorps
Souris
Clonalité
Toutes les clonalités sur TNNI3 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers TNNI3 Anticorps
Cet anticorp TNNI3 est non-conjugé
Application
Tous les applications à travers TNNI3 Anticorps.
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificité
This antibody reacts equally with free cardiac Troponin I (cTnI) and cTnI forming complexes with other troponin components. Not affected by heparin, phosphorylation and oxidation. Recognizes an epitope located between amino acid residues 186 and 192 of cTnI. Cross-reacts with skeletal troponin I from human, rat and mouse.
Réactivité croisée (Details)
Also reacts to: skeletal
Purification
Protein A chromatography
Pureté
> 90 % pure (SDS-PAGE)
Immunogène
Free human cardiac troponin I
Clone
C5
Isotype
IgG2b
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
3.5mg/mL (Sigma protein assay kit)
Buffer
PBS, pH 7.4 containing 0,09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C.
Références pour anticorps anti-TNNI3 (ABIN272322)
(cache)
Laube, Heister, Scholz, Borchardt, Braun : "Re-programming of newt cardiomyocytes is induced by tissue regeneration. " dans: Journal of cell science , Vol. 119 , Issue Pt 22 , pp. 4719-29 , (2007 ) (PubMed ).
Détails sur TNNI3
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Antigène
TNNI3
(Cardiac Troponin I (TNNI3))
Autre désignation
Cardiac Troponin I (TNNI3 Produits )
Synonymes
anticorps CMD1FF, anticorps CMD2A, anticorps CMH7, anticorps RCM1, anticorps TNNC1, anticorps cTnI, anticorps CMD1Z, anticorps CMH13, anticorps TN-C, anticorps TNC, anticorps TNNC, anticorps Tn1, anticorps TnIc, anticorps ctnIc, anticorps XTnIc, anticorps c-troponin, anticorps cTNT, anticorps cmh7, anticorps ctni, anticorps tnnc1, anticorps TNNI3, anticorps TnI, anticorps cTNI, anticorps AI874626, anticorps TnC, anticorps cTnC, anticorps tncc, anticorps Tncc, anticorps troponin I3, cardiac type, anticorps troponin C1, slow skeletal and cardiac type, anticorps troponin I, cardiac 3, anticorps troponin I type 3 (cardiac), anticorps troponin I3, cardiac type S homeolog, anticorps troponin I3, cardiac type L homeolog, anticorps cardiac troponin I, anticorps troponin C, cardiac/slow skeletal, anticorps TNNI3, anticorps TNNC1, anticorps Tnni3, anticorps tnni3.S, anticorps tnni3.L, anticorps tnni3, anticorps LOC100462680, anticorps Tnnc1
Sujet
Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.Synonyms: TNNC1, TNNI3
ID gène
7137
NCBI Accession
NP_000354
UniProt
P19429
Vus récemment
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