TNNI3 anticorps

N° du produit ABIN272322

Cité dans 1 publication. Cet anticorps anti-TNNI3 Monoclonal Souris (Clone C5) (ABIN272322) détecte spécifiquement TNNI3 dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain, Souris, Boeuf (Vache), Lapin, Poisson, Poulet et Amphibien.

Aperçu rapide pour TNNI3 anticorps (ABIN272322)

Antigène: TNNI3 (Cardiac Troponin I (TNNI3))

Reactivité: Humain, Souris, Boeuf (Vache), Lapin, Poisson, Poulet, Amphibien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TNNI3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: C5

Détail du produit anti-TNNI3 anticorps

Specificité: This antibody reacts equally with free cardiac Troponin I (cTnI) and cTnI forming complexes with other troponin components. Not affected by heparin, phosphorylation and oxidation. Recognizes an epitope located between amino acid residues 186 and 192 of cTnI. Cross-reacts with skeletal troponin I from human, rat and mouse.

Réactivité croisée (Details): Also reacts to: skeletal

Purification: Protein A chromatography

Pureté: > 90 % pure (SDS-PAGE)

Immunogène: Free human cardiac troponin I

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 3.5mg/mL (Sigma protein assay kit)

Buffer: PBS, pH 7.4 containing 0,09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Références pour anticorps anti-TNNI3 (ABIN272322)

Laube, Heister, Scholz, Borchardt, Braun: "Re-programming of newt cardiomyocytes is induced by tissue regeneration." dans: Journal of cell science, Vol. 119, Issue Pt 22, pp. 4719-29, (2007) (PubMed).

Détails sur TNNI3

Antigène: TNNI3 (Cardiac Troponin I (TNNI3))

Autre désignation: Cardiac Troponin I

Sujet: Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.Synonyms: TNNC1, TNNI3

ID gène: 7137

NCBI Accession: NP_000354

UniProt: P19429