PSMA anticorps

N° du produit ABIN2729884

Cet anticorps anti-PSMA Monoclonal Souris (Clone 3H5) (ABIN2729884) détecte spécifiquement PSMA dans WB, IHC, FACS et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour PSMA anticorps (ABIN2729884)

Antigène: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PSMA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 3H5

Détail du produit anti-PSMA anticorps

Attributs du produit: Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human FOLH1(NP_004467) produced in HEK293T cell.

Isotype: IgG1

Information d'application

Indications d'application: WB 1:500~1000, IHC 1:150, IF 1:100, FLOW 1:100,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur PSMA

Antigène: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Autre désignation: FOLH1

Sujet: This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.

Poids moléculaire: 84.2 kDa

ID gène: 2346

NCBI Accession: NM_004476

HGNC: 2346