SAMHD1 anticorps

N° du produit ABIN2731369

Détail du produit anti-SAMHD1 anticorps

Antigène: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SAMHD1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Attributs du produit: Homo sapiens SAM domain and HD domain 1 (SAMHD1)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human SAMHD1 (NP_056289) produced in HEK293T cell.

Clone: 2D7

Isotype: IgG2b

Information d'application

Indications d'application: WB 1:2000, IF 1:100, FLOW 1:100

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-SAMHD1 (ABIN2731369)

Jeong, Park, Ahn, Ahn: "Inhibition of hepatitis B virus replication by a dNTPase-dependent function of the host restriction factor SAMHD1." dans: Virology, Vol. 495, pp. 71-8, (2016) (PubMed).

Hertoghs, van der Aar, Setiawan, Kootstra, Gringhuis, Geijtenbeek: "SAMHD1 degradation enhances active suppression of dendritic cell maturation by HIV-1." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 9, pp. 4431-7, (2015) (PubMed).

Pan, Pan, Weng, Zhao, Zhang, Wang, Lv, Jiang, Zheng, Xia: "Annexin A3 promotes tumorigenesis and resistance to chemotherapy in hepatocellular carcinoma." dans: Molecular carcinogenesis, Vol. 54, Issue 8, pp. 598-607, (2015) (PubMed).

Zhang, Bloch, Nguyen, Kim, Landau: "SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells." dans: PLoS ONE, Vol. 9, Issue 2, pp. e89558, (2014) (PubMed).

Détails sur SAMHD1

Antigène: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Autre désignation: SAMHD1 (SAMHD1 Produits)

Synonymes: anticorps CHBL2, anticorps DCIP, anticorps HDDC1, anticorps MOP-5, anticorps SBBI88, anticorps si:dkeyp-44b8.8, anticorps E330031J07Rik, anticorps Mg11, anticorps SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1, anticorps SAM domain and HD domain 1, anticorps SAM domain and HD domain, 1, anticorps SAMHD1, anticorps samhd1, anticorps Samhd1

Sujet: This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. COMPLETENESS: complete on the 3' end.

Poids moléculaire: 72 kDa

ID gène: 25939

NCBI Accession: NM_015474

HGNC: 25939