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Cytokeratin 19 anticorps (AA 379-392)

Cet anticorps anti-Cytokeratin 19 est un anticorps Lapin Polyclonal détectant Cytokeratin 19 dans WB, IHC, IHC (p), ICC et IHC (fro). Adapté pour Humain.
N° du produit ABIN2742480

Aperçu rapide pour Cytokeratin 19 anticorps (AA 379-392) (ABIN2742480)

Antigène

Voir toutes Cytokeratin 19 (KRT19) Anticorps
Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Reactivité

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Humain

Hôte

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Lapin

Clonalité

  • 188
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Polyclonal

Conjugué

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Cet anticorp Cytokeratin 19 est non-conjugé

Application

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Épitope

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    AA 379-392

    Specificité

    Human KRT19 / CK19 / Cytokeratin 19

    Purification

    Immunoaffinity purified

    Immunogène

    A synthetic peptide corresponding to a sequence at the C-terminus of human Cytokeratin 19 (379-392aa YRSLLEGQEDHYNN). Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%), Orangutan, Marmoset, Mouse (93%), Baboon, Rat, Rabbit (86%).

    Type of Immunogen: Synthetic peptide

    Isotype

    IgG
  • Indications d'application

    Approved: ICC (0.5 - 1 μg/mL), IHC, IHC-Fr (0.5 - 1 μg/mL), IHC-P (0.5 - 1 μg/mL), WB (0.5 - 1 μg/mL)

    Usage: Keratin, type I cytoskeletal 19 is a protein that in humans is encoded by the KRT19 gene.The protein encoded by this gene is a member of the keratin family. It is specifically expressed in the periderm, the transiently superficial layer that envelops the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. Due to its high sensitivity, KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. Keratin 19 is often used together with keratin 8 and keratin 18 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Sterile distilled water

    Concentration

    Lot specific

    Buffer

    Lyophilized from PBS, 2.5 % BSA, 0.025 % sodium azide/thimerosal.

    Agent conservateur

    Sodium azide, Thimerosal (Merthiolate)

    Précaution d'utilisation

    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid freeze/thaw cycles.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.
  • Antigène

    Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

    Autre désignation

    KRT19 / CK19 / Cytokeratin 19

    Sujet

    Name/Gene ID: KRT19

    Synonyms: KRT19, CK19, Cytokeratin 19, Cytokeratin-19, Keratin 19, Keratin-19, CK-19, K19, K1CS, Keratin, type I, 40-kd

    ID gène

    3880
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