TIMP3 anticorps (AA 198-211)

N° du produit ABIN2744876

L’anticorps Lapin Polyclonal anti-TIMP3 a été validé pour WB et ELISA. Il convient pour détecter TIMP3 dans des échantillons de Humain, Rat, Boeuf (Vache), Chien, Porc, Mouton, Singe, Chimpanzé et Gibbon.

Aperçu rapide pour TIMP3 anticorps (AA 198-211) (ABIN2744876)

Antigène: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Porc, Mouton, Singe, Chimpanzé, Gibbon

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMP3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TIMP3 anticorps

Épitope: AA 198-211

Specificité: Human TIMP3

Purification: Immunoaffinity purified

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human TIMP3(198-211aa WAPPDKSIINATDP). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Ferret, Sheep, Cat, Bovine, Pig, Dog (100%), Mouse, Bat, Hamster, Opossum, Zebra finch, Chicken, Lizard (93%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: ELISA (0.1 - 0.5 μg/mL), WB (0.5 - 1 μg/mL)

Usage: The tissue inhibitors of metalloproteinases(TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy(SFD).

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Sterile distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS, 2.5 % BSA, 0.025 % sodium azide/thimerosal.

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.

Détails sur TIMP3

Antigène: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Autre désignation: TIMP3

Sujet: Name/Gene ID: TIMP3

Synonyms: TIMP3, HSMRK222, K222TA2, MIG-5 protein, K222, SFD, Metalloproteinase inhibitor 3, Protein MIG-5, TIMP-3

ID gène: 7078