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BMF anticorps

Cet anticorps Rat Monoclonal détecte spécifiquement BMF dans WB, IP et FACS. Il présente une réactivité envers Humain et Souris.
N° du produit ABIN2745518

Aperçu rapide pour BMF anticorps (ABIN2745518)

Antigène

Voir toutes BMF Anticorps
BMF (Bcl2 Modifying Factor (BMF))

Reactivité

  • 35
  • 15
  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris

Hôte

  • 31
  • 3
  • 2
Rat

Clonalité

  • 30
  • 6
Monoclonal

Conjugué

  • 24
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp BMF est non-conjugé

Application

  • 28
  • 16
  • 11
  • 7
  • 4
  • 3
  • 3
  • 3
  • 2
Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)

Clone

9G10
  • Specificité

    Recognizes human and mouse Bmf.

     Réactivité croisée

    Humain, Souris

    Réactivité croisée (Details)

    Detects several cross-reactivity bands of unknown identity in mice by western blot.

    Pureté

    >95 % (SDS-PAGE)

    niveau d'endotoxine

    <0.1EU/μg purified protein (LAL test, Lonza).

    Immunogène

    Recombinant mouse Bmf.

    Isotype

    IgG2a
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    In PBS containing 0.02 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.

    Date de péremption

    12 months
  • Antigène

    BMF (Bcl2 Modifying Factor (BMF))

    Autre désignation

    Bmf

    Sujet

    Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.

    UniProt

    Q96LC9
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