Podoplanin anticorps
Aperçu rapide pour Podoplanin anticorps (ABIN2745557)
Antigène
Voir toutes Podoplanin (PDPN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Specificité
- Recognizes mouse podoplanin.
-
Réactivité croisée
- Souris
-
Aucune reactivité croisée
- Humain
-
Réactivité croisée (Details)
- Does not cross-react with human podoplanin.
-
Purification
- Protein G purified.
-
Immunogène
- Murine thymic stromal cell line.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Centrifuge vial prior to opening. Reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL.
-
Concentration
- Lot specific
-
Buffer
- Lyophilized.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. -
Date de péremption
- 6 months
-
-
- Podoplanin (PDPN)
-
Autre désignation
- Podoplanin
-
Sujet
- Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.
-
Pathways
- Dicarboxylic Acid Transport
Antigène
-