PDE4D PKA Site (AA 50-100), (N-Term), (phosphorylated) anticorps

N° du produit ABIN2747156

Cet anticorps Lapin Polyclonal détecte spécifiquement PDE4D PKA Site dans ELISA, IHC (p), IP et WB. Il présente une réactivité avec des échantillons de Humain, Souris et Rat. Il a été cité dans 4+ publications.

Aperçu rapide pour PDE4D PKA Site (AA 50-100), (N-Term), (phosphorylated) anticorps (ABIN2747156)

Antigène: PDE4D PKA Site

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)

Détail du produit

Épitope: AA 50-100, N-Term, phosphorylated

Purification: Affinity Purified

Immunogène: Phosphorylated synthetic peptide selective for PDE4D PKA site taken within amino acid region 50-100 on human PDE4D8 protein.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.57 μg/μL

Référence

Fu, Kim, Soto, De Arcangelis, DiPilato, Liu, Xu, Shi, Zhang, Xiang: "A long lasting β1 adrenergic receptor stimulation of cAMP/protein kinase A (PKA) signal in cardiac myocytes." dans: The Journal of biological chemistry, Vol. 289, Issue 21, pp. 14771-81, (2014) (PubMed).

Mahavadi, Nalli, Kumar, Hu, Kuemmerle, Grider, Murthy: "Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle." dans: American journal of physiology. Cell physiology, Vol. 307, Issue 4, pp. C402-11, (2014) (PubMed).

Murthy, Sriwai: "Stimulatory phosphorylation of cAMP-specific PDE4D5 by contractile agonists is mediated by PKC-dependent inactivation of protein phosphatase 2A." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 294, Issue 1, pp. G327-35, (2008) (PubMed).

Zhu, Kelly, Vemavarapu, Thompson, Strada: "Activation and induction of cyclic AMP phosphodiesterase (PDE4) in rat pulmonary microvascular endothelial cells." dans: Biochemical pharmacology, Vol. 68, Issue 3, pp. 479-91, (2004) (PubMed).

Détail du antigène

Antigène: PDE4D PKA Site

UniProt: Q08499