CD2 anticorps

N° du produit ABIN2749021

Cet anticorps anti-CD2 est un anticorps Souris Monoclonal détectant CD2 dans FACS et Func. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour CD2 anticorps (ABIN2749021)

Antigène: CD2

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD2 est non-conjugé

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: TS1-8

Détail du produit anti-CD2 anticorps

Fonction: Anti-Hu CD2 Purified Low Endotoxin

Specificité: The mouse monoclonal antibody TS1/8 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

niveau d'endotoxine: Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

Immunogène: Cytotoxic T lymphocytes

Isotype: IgG1 kappa

Information d'application

Indications d'application: Functional application: Blocking.
Flow cytometry: Recommended dilution: 1-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-CD2 (ABIN2749021)

Zhang, Dai, Li, Zhuang: "Tracking proliferative history in lymphocyte development with cre-mediated sister chromatid recombination." dans: PLoS genetics, Vol. 9, Issue 10, pp. e1003887, (2013) (PubMed).

Détails sur CD2

Antigène: CD2

Autre désignation: CD2

Sujet: CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC

ID gène: 914

UniProt: P06729