CD235a/GYPA anticorps (PE)

N° du produit ABIN2749119

L’anticorps Souris Monoclonal anti-CD235a/GYPA a été validé pour FACS. Il convient pour détecter CD235a/GYPA dans des échantillons de Humain et Rat. Il y a 4+ publications disponibles.

Aperçu rapide pour CD235a/GYPA anticorps (PE) (ABIN2749119)

Antigène: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD235a/GYPA est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: JC159

Détail du produit anti-CD235a/GYPA anticorps (PE)

Fonction: Anti-Hu CD235a PE

Specificité: The mouse monoclonal antibody JC159 recognizes an epitope between amino acids 27 and 40 of the extracellular portion of CD235a (glycophorin A), a sialoglycoprotein expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL. The antibody does not react with glycophorin B.

Réactivité croisée (Details): Human, Rat

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: Membrane preparation from splenic hairy cell leukemia

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Références pour anticorps anti-CD235a/GYPA (PE) (ABIN2749119)

Yamauchi, Takenaka, Urata, Shima, Kikushige, Tokuyama, Iwamoto, Nishihara, Iwasaki, Miyamoto, Honma, Nakao, Matozaki, Akashi: "Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment." dans: Blood, Vol. 121, Issue 8, pp. 1316-25, (2013) (PubMed).

Beck, Jagodzinski, Eller, Thelian, Matyas, Kunz, Alving: "Platelets and erythrocyte-bound platelets bind infectious HIV-1 in plasma of chronically infected patients." dans: PLoS ONE, Vol. 8, Issue 11, pp. e81002, (2013) (PubMed).

Alijotas-Reig, Palacio-Garcia, Llurba, Vilardell-Tarres: "Cell-derived microparticles and vascular pregnancy complications: a systematic and comprehensive review." dans: Fertility and sterility, Vol. 99, Issue 2, pp. 441-9, (2013) (PubMed).

Maijenburg, Kleijer, Vermeul, Mul, van Alphen, van der Schoot, Voermans: "The composition of the mesenchymal stromal cell compartment in human bone marrow changes during development and aging." dans: Haematologica, Vol. 97, Issue 2, pp. 179-83, (2012) (PubMed).

Détails sur CD235a/GYPA

Antigène: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Autre désignation: CD235a

Sujet: Glycophorin A (MNS blood group),CD235a (glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to CD235b (glycophorin B, GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, a Streptococcus adhesin.,Glycophorin A, GYPA, GPA, PAS-2, Sialoglycoprotein alpha, MN sialoglycoprotein, GPSAT, GPErik, MSN blood group

ID gène: 2993

UniProt: P02724

Pathways: Maintenance of Protein Location